Article
A genome-wide perspective of human diversity and its implications in infectious disease.
Cold Spring Harbor perspectives in medicine - 1 Jan 2013
Manry Jérémy, Quintana-Murci Lluis
Abstract excerpt
Progress in genomic technologies, such as DNA arrays and next-generation sequencing, is allowing systematic characterization of the degree of human genetic variation at the scale of individual genomes. Public efforts, such as the International HapMap Project and the 1000 Genomes Project, have provided a realistic picture of the levels of genetic diversity in individuals and populations. These genomic techniques...
Topics
- Communicable Diseases
- Disease Progression
- Exome
- Gene Expression Profiling
- Genetic Predisposition to Disease
- Genetic Variation
- Genome, Human
- Genome-Wide Association Study
- Humans
- Rare Diseases