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Article

European genetic diversity and susceptibility to pathogens.

Human heredity - 1 Jan 2013

McLaren Paul J, Fellay Jacques, Telenti Amalio

Abstract excerpt

Infectious diseases, both in their endemic and epidemic forms, have shaped the human genome. Ecology has also contributed to geographically constrained pressures on human populations. There are now multiple examples of population-specific genetic variants that modulate susceptibility to infection - several of which have been observed solely in Europeans. The pathogen genome also mutates and adapts to individuals...

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PMID: 24861863
DOI: 10.1159/000357758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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