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Article

The effects of hyaluronic acid hydrogels with tunable mechanical properties on neural progenitor cell differentiation.

Biomaterials - 1 May 2010

Seidlits Stephanie K, Khaing Zin Z, Petersen Rebecca R, Nickels Jonathan D, Vanscoy Jennifer E, Shear Jason B, Schmidt Christine E

Abstract excerpt

We report the ability to direct the differentiation pathway of neural progenitor cells (NPCs) within hydrogels having tunable mechanical properties. By modifying the polymeric sugar hyaluronic acid (HA), a major extracellular matrix component in the fetal mammalian brain, with varying numbers of photocrosslinkable methacrylate groups, hydrogels could be prepared with bulk compressive moduli spanning the threefold...

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Identifiers

PMID: 20171731
DOI: 10.1016/j.biomaterials.2010.01.125

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GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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