Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional interactions between homologous conditional killer systems of plasmid and chromosomal origin.

FEMS microbiology letters - 1 Jul 1997

Santos-Sierra S, Giraldo R, Díaz-Orejas R

Abstract excerpt

parD and chpA are homologous conditional killer systems of plasmid and chromosomal origin, respectively, encoding a killer protein (Kid and ChpAK) and an antidote (Kis and ChpAI). Here it is shown that these systems can functionally interact. A multicopy chpA recombinant partially complements two mutations in the antidote of the parD system. These mutations affect either autoregulation or neutralization of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Operon

Share to Plasmids

Source

Identifiers

PMID: 9228770
DOI: 10.1111/j.1574-6968.1997.tb10408.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Functional interactions between homologous conditional killer systems of plasmid and chromosomal origin.PMID 9228770Read ↗

Genetic identification of two functional regions in the antitoxin of the parD killer system of plasmid R1.Semantic proximity Read ↗

Identification of residues of the kid toxin involved in autoregulation of the parD system.Semantic proximity Read ↗

Structural and functional comparison between the stability systems ParD of plasmid R1 and Ccd of plasmid F.Semantic proximity Read ↗

Kis antitoxin couples plasmid R1 replication and parD (kis,kid) maintenance modules.Semantic proximity Read ↗

Combining the hok/sok, parDE, and pnd postsegregational killer loci to enhance plasmid stability.Semantic proximity Read ↗

F plasmid CcdB killer protein: ccdB gene mutants coding for non-cytotoxic proteins which retain their regulatory functions.Semantic proximity Read ↗

A mutation that decreases the efficiency of plasmid R1 replication leads to the activation of parD, a killer stability system of the plasmid.Semantic proximity Read ↗

The divergent promoters mediating transcription of the par locus of plasmid RP4 are subject to autoregulation.Semantic proximity Read ↗

Partitioning of plasmid R1. The ParM protein exhibits ATPase activity and interacts with the centromere-like ParR-parC complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.