Article
An efficient approach to isolate STAT regulated enhancers uncovers STAT92E fundamental role in Drosophila tracheal development.
Developmental biology - 15 Apr 2010
Sotillos Sol, Espinosa-Vázquez Jose Manuel, Foglia Filippo, Hu Nan, Hombría James Castelli-Gair
Abstract excerpt
The ventral veinless (vvl) and trachealess (trh) genes are determinants of the Drosophila trachea. Early in development both genes are independently activated in the tracheal primordia by signals that are ill defined. Mutants blocking JAK/STAT signaling at any level do not form a tracheal tree su...
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