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Article

Lifelong protection from global cerebral ischemia and reperfusion in long-lived Mclk1(+/)(-) mutants.

Experimental neurology - 1 Jun 2010

Zheng Huaien, Lapointe Jérôme, Hekimi Siegfried

Abstract excerpt

To achieve a long life span, animals must be resistant to various injuries as well as avoid or delay lethality from age-dependent diseases. Reduced expression of the mitochondrial enzyme CLK-1/MCLK1 (a.k.a. Coq7), a mitochondrial hydroxylase that is necessary for the biosynthesis of ubiquinone (U...

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Identifiers

PMID: 20170652
DOI: 10.1016/j.expneurol.2010.02.002
PMCID: PMC4053415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20170652-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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