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Article

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells

28 Apr 2016

Abstract excerpt

Glioblastoma (GBM) is one of the most aggressive types of cancer with limited therapeutic options and unfavorable prognosis. Stemness and non-classical epithelial-to-mesenchymal transition (ncEMT) features underlie the switch from normal to neoplastic states as well as resistance of tumor clones to current therapies. Therefore, identification of ligand/receptor systems maintaining this privileged state is needed...

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PMID: 27124583
DOI: 10.1038/cddis.2016.102

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