The major locus for mouse adenovirus susceptibility maps to genes of the hematopoietic cell surface-expressed LY6 family.

doi:10.4049/jimmunol.0903363

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Article

The major locus for mouse adenovirus susceptibility maps to genes of the hematopoietic cell surface-expressed LY6 family.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2010

Spindler Katherine R, Welton Amanda R, Lim Efrem S, Duvvuru Suman, Althaus Irene W, Imperiale Jennifer E, Daoud Adam I, Chesler Elissa J

Abstract excerpt

Susceptibility to mouse adenovirus type 1 is associated with the major quantitative trait locus Msq1. Msq1 was originally mapped to a 13-Mb region of mouse chromosome (Chr) 15 in crosses between SJL/J and BALB/cJ inbred mice. We have now narrowed Msq1 to a 0.75-Mb interval from 74.68 to 75.43 Mb, defined by two anonymous markers, rs8259436 and D15Spn14, using data from 1396 backcross mice. The critical interval...

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PMID: 20164425
DOI: 10.4049/jimmunol.0903363
PMCID: PMC2832721

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