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Article

Polymorphisms of genes encoding tumor necrosis factor-alpha, interleukin-10, cluster of differentiation-14 and interleukin-1ra in critically ill patients.

Journal of critical care - 1 Sept 2010

Surbatovic Maja, Grujic Krasimirka, Cikota Bojana, Jevtic Miodrag, Filipovic Nikola, Romic Predrag, Strelic Natasa, Magic Zvonko

Abstract excerpt

PURPOSE: The aim of the study was to determine whether distributions of tumor necrosis factor (TNF)-α(308), interleukin (IL)-10(1082), CD14(159), and IL-1ra gene intron 2 genotypes in critically ill patients are associated with outcome, underlying cause of sepsis, and type of microorganism. MATERIALS AND METHODS: Blood samples from 106 critically ill white patients were genotyped by method based on polymerase...

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Identifiers

PMID: 20163933
DOI: 10.1016/j.jcrc.2009.12.003

Genes

TNF

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