Article
Association of polymorphisms of IL and CD14 genes with acute severe pancreatitis and septic shock.
World journal of gastroenterology - 28 Jul 2005
Zhang Dian-Liang, Zheng Hong-Mei, Yu Bao-Jun, Jiang Zhi-Wei, Li Jie-Shou
Abstract excerpt
AIM: To investigate IL-1beta+3 594 in the 5th intron, IL-10-1 082 and CD14-159 polymorphisms in patients with acute pancreatitis (AP) and septic shock. METHODS: The study included 215 patients (109 with acute severe pancreatitis (SAP), 106 with acute mild pancreatitis (MAP)) and 116 healthy volunteers. Genomic DNA was prepared from peripheral blood leukocytes. Genotypes and allele frequencies were determined in...
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