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Article

A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels.

American journal of human genetics - 12 Mar 2010

Xing Chao, Cohen Jonathan C, Boerwinkle Eric

Abstract excerpt

Association signals in GWAS are usually prioritized solely by p values. Here, we attempt to improve the power of GWAS by using a weighted false discovery rate control procedure to detect associations of low-frequency variants with effect sizes similar to or even larger than those of common variants. We used the Affymetrix Genome-Wide Human SNP Array 6.0 to test for association with fasting glucose levels in the...

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Biostatistics
Black or African American
Blood Glucose
Fasting
Hepatocyte Nuclear Factor 3-beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

Oligonucleotide Array Sequence Analysis

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Identifiers

PMID: 20152958
DOI: 10.1016/j.ajhg.2010.01.025
PMCID: PMC2833364

Genes

FOXA2

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