Article
Genetic variants of FOXA2: risk of type 2 diabetes and effect on metabolic traits in North Indians.
Journal of human genetics - 1 Jan 2008
Tabassum Rubina, Chavali Sreenivas, Dwivedi Om Prakash, Tandon Nikhil, Bharadwaj Dwaipayan
Abstract excerpt
Here, we examined the association of genetic variants of FOXA2, an upstream activator of the beta-cell transcription factor network, with type 2 diabetes and related phenotypes in North India. We genotyped three SNPs (rs1212275, rs1055080, rs6048205) and the (TCC)( n ) repeat polymorphism in 1,656 participants comprising 1,031 patients with type 2 diabetes and 625 controls. SNPs rs1212275 and rs6048205 were...
