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Article

Podocyte-specific expression of tamoxifen-inducible Cre recombinase in mice

11 Feb 2010

Abstract excerpt

BACKGROUND: Podocytes play an important role in maintaining normal glomerular function. A podocyte-specific conditional knockout technology has been established by the use of transgenic mice expressing a podocyte-specific Cre recombinase to clarify the role of genes expressed in the podocytes. However, it may be difficult to examine the role of genes in certain pathologic conditions using conventional...

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PMID: 20150167
DOI: 10.1093/ndt/gfq029

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