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Article

Inducible gene silencing in podocytes: a new tool for studying glomerular function.

Journal of the American Society of Nephrology : JASN - 1 Mar 2003

Bugeon Laurence, Danou Aliki, Carpentier David, Langridge Paul, Syed Nelofer, Dallman Margaret J

Abstract excerpt

Glomerular filtration is one of the primary functions of the kidney. Podocytes, a highly specialized cell type found in glomeruli, are believed to play a critical role in that function. Null mutations of genes expressed in podocytes like WT1, nephrin, and NEPH1 result in an embryo and perinatal lethal phenotype and therefore do not allow the functional analysis of these genes in the adult kidney. Here is...

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Identifiers

PMID: 12595517
DOI: 10.1097/01.asn.0000050222.86847.ea

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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