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Identification and characterization of a glomerular-specific promoter from the human nephrin gene

1 Dec 2000

Abstract excerpt

Podocytes are highly specialized cells that make up a major portion of the glomerular filtration barrier in the kidney. They are also believed to play a pivotal role in the progression of chronic renal disease due to diverse causes that include diabetes (3, 20, 24) and aging (1, 7). Despite the importance of podocytes for kidney function and disease, studies of this cell type have been hindered due to a lack of...

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PMID: 11097620
DOI: 10.1152/ajprenal.2000.279.6.f1027

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