Article
Genome-wide linkage of obstructive sleep apnoea and high-density lipoprotein cholesterol in a Filipino family: bivariate linkage analysis of obstructive sleep apnoea.
Journal of sleep research - 1 Jun 2010
Relf Bronwyn L, Larkin Emma K, De Torres Carina, Baur Louise A, Christodoulou John, Waters Karen A
Abstract excerpt
Increasing evidence supports an association between obstructive sleep apnoea (OSA) and metabolic syndrome (MeS) in both children and adults, suggesting a genetic component. However, the genetic relationship between the diseases remains unclear. We performed a bivariate linkage scan on a single Filipino family with a high prevalence of OSA and MeS to explore the genetic pathways underlying these diseases. A large...
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