Article
A whole-genome scan for obstructive sleep apnea and obesity.
American journal of human genetics - 1 Feb 2003
Palmer Lyle J, Buxbaum Sarah G, Larkin Emma, Patel Sanjay R, Elston Robert C, Tishler Peter V, Redline Susan
Abstract excerpt
Obstructive sleep apnea (OSA) is a common, chronic, complex disease associated with serious cardiovascular and neuropsychological sequelae and with substantial social and economic costs. Along with male gender, obesity is the most characteristic feature of OSA in adults. To identify susceptibility loci for OSA, we undertook a 9-cM genome scan in 66 white pedigrees (n=349 subjects) ascertained on the basis of...
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