Article
Whole genome scan for obstructive sleep apnea and obesity in African-American families.
American journal of respiratory and critical care medicine - 15 Jun 2004
Palmer Lyle J, Buxbaum Sarah G, Larkin Emma K, Patel Sanjay R, Elston Robert C, Tishler Peter V, Redline Susan
Abstract excerpt
Obstructive sleep apnea (OSA) is a common, chronic disease associated with obesity. OSA and obesity are both prevalent in African Americans, who are also at increased risk for secondary complications. To identify susceptibility loci for OSA, we undertook a 9-centimorgans genome scan in 59 African-American pedigrees ascertained on the basis of either an affected individual with laboratory-confirmed disease or a...
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