Article
Genome-wide linkage scan for the metabolic syndrome in the HERITAGE Family Study.
The Journal of clinical endocrinology and metabolism - 1 Dec 2003
Loos Ruth J F, Katzmarzyk Peter T, Rao D C, Rice Treva, Leon Arthur S, Skinner James S, Wilmore Jack H, Rankinen Tuomo, Bouchard Claude
Abstract excerpt
The metabolic syndrome involves multiple and interactive effects of genes and environmental factors. To identify chromosomal regions encoding genes possibly predisposing to the metabolic syndrome, we performed a genome-wide scan with 456 white and 217 black participants from 204 nuclear families of the HERITAGE Family Study, using regression-based, single- and multipoint linkage analyses on 509 markers. A...
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