Article
Association of genetic loci with sleep apnea in European Americans and African-Americans: the Candidate Gene Association Resource (CARe).
PloS one - 1 Jan 2012
Patel Sanjay R, Goodloe Robert, De Gourab, Kowgier Matthew, Weng Jia, Buxbaum Sarah G, Cade Brian, Fulop Tibor, Gharib Sina A, Gottlieb Daniel J, Hillman David, Larkin Emma K, Lauderdale Diane S, Li Li, Mukherjee Sutapa, Palmer Lyle, Zee Phyllis, Zhu Xiaofeng, Redline Susan
Abstract excerpt
Although obstructive sleep apnea (OSA) is known to have a strong familial basis, no genetic polymorphisms influencing apnea risk have been identified in cross-cohort analyses. We utilized the National Heart, Lung, and Blood Institute (NHLBI) Candidate Gene Association Resource (CARe) to identify sleep apnea susceptibility loci. Using a panel of 46,449 polymorphisms from roughly 2,100 candidate genes on a...
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