Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thrombin generation in haemophilia A patients with mutations causing factor VIII assay discrepancy.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jul 2010

Gilmore R, Harmon S, Gannon C, Byrne M, O'Donnell J S, Jenkins P V

Abstract excerpt

Up to 40% of patients with mild haemophilia A have a discrepancy whereby factor VIII (FVIII) measurements by a two-stage chromogenic assay (FVIII:C(CH)) are disproportionately reduced compared with the FVIII one-stage clotting value (FVIII:C). Which assay best reflects the coagulation potential a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Blood Coagulation Tests
Share to Factor VIII

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemophilia A

Share to Mutation

Share to Phenotype

Share to Thrombin

Share to Young Adult

Source

Identifiers

PMID: 20148980
DOI: 10.1111/j.1365-2516.2009.02190.x

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20148980-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thrombin generation in haemophilia A patients with mutations causing factor VIII assay discrepancy.PMID 20148980Read ↗

Mild hemophilia A with factor VIII assay discrepancy: using thrombin generation assay to assess the bleeding phenotype.Semantic proximity Read ↗

Thrombin generation assay using factor IXa as a trigger to quantify accurately factor VIII levels in haemophilia A.Semantic proximity Read ↗

Haemophilia A mutations in patients with non-severe phenotype associated with a discrepancy between one-stage and chromogenic factor VIII activity assays.Semantic proximity Read ↗

Genetics and Hemostatic Potential in Persons with Mild to Moderate Hemophilia A with a Discrepancy between One-Stage and Chromogenic FVIII Assays.Semantic proximity Read ↗

Diagnosis and management challenges in patients with mild haemophilia A and discrepant FVIII measurements.Semantic proximity Read ↗

Discrepancies between the one-stage clotting assay and the chromogenic assay in haemophilia B.Semantic proximity Read ↗

Discrepancy between one-stage and chromogenic factor VIII activity assay results can lead to misdiagnosis of haemophilia A phenotype.Semantic proximity Read ↗

Comparing one stage, chromogenic assay results and discrepancies with bleeding phenotype and genetic variants in females with hemophilia A.Semantic proximity Read ↗

One-stage and chromogenic FVIII:C assay discrepancy in mild haemophilia A and the relationship with the mutation and bleeding phenotype.Semantic proximity Read ↗

Genetic analysis of non-severe hemophilia A phenotype with A discrepancy between one-stage and chromogenic factor VIII activity assays.Semantic proximity Read ↗

In vitro kinetics of factor VIII activity in patients with mild haemophilia A and a discrepancy between one-stage and two-stage factor VIII assay results.Semantic proximity Read ↗

p.Tyr365Cys change in factor VIII: haemophilia A, but not as we know it.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.