Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Haemophilia A mutations in patients with non-severe phenotype associated with a discrepancy between one-stage and chromogenic factor VIII activity assays.

Thrombosis and haemostasis - 5 May 2014

Pavlova Anna, Delev Daniel, Pezeshkpoor Behnaz, Müller Jens, Oldenburg Johannes

Abstract excerpt

About one-third of patients with non-severe haemophilia A (HA) show a discrepancy of factor (F)VIII activity (FVIII:C) measured by one-stage (FVIII:C1st), two-stage assays or the chromogenic method (FVIII:Cchr). The aim of the study was to characterise the mutation profile in patients with FVIII:C assay discrepancies. FVIII:C discrepancy was considered significant if the calculated ratio between FVIII:C1st and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation Tests
Share to Disease Progression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Early Diagnosis

Share to Factor VIII

Share to Hemophilia A

Share to Mutation, Missense

Share to Observer Variation

Share to Protein Conformation

Source

Identifiers

PMID: 24452774
DOI: 10.1160/TH13-08-0690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Haemophilia A mutations in patients with non-severe phenotype associated with a discrepancy between one-stage and chromogenic factor VIII activity assays.PMID 24452774Read ↗

Genetic analysis of non-severe hemophilia A phenotype with A discrepancy between one-stage and chromogenic factor VIII activity assays.Semantic proximity Read ↗

One-stage and chromogenic FVIII:C assay discrepancy in mild haemophilia A and the relationship with the mutation and bleeding phenotype.Semantic proximity Read ↗

Diagnosis and management challenges in patients with mild haemophilia A and discrepant FVIII measurements.Semantic proximity Read ↗

Discrepancy between one-stage and chromogenic factor VIII activity assay results can lead to misdiagnosis of haemophilia A phenotype.Semantic proximity Read ↗

Genetics and Hemostatic Potential in Persons with Mild to Moderate Hemophilia A with a Discrepancy between One-Stage and Chromogenic FVIII Assays.Semantic proximity Read ↗

Comparing one stage, chromogenic assay results and discrepancies with bleeding phenotype and genetic variants in females with hemophilia A.Semantic proximity Read ↗

Mild hemophilia A with factor VIII assay discrepancy: using thrombin generation assay to assess the bleeding phenotype.Semantic proximity Read ↗

Discrepancies between the one-stage clotting assay and the chromogenic assay in haemophilia B.Semantic proximity Read ↗

p.Tyr365Cys change in factor VIII: haemophilia A, but not as we know it.Semantic proximity Read ↗

MUTATIONS IN A SUBGROUP OF PATIENTS WITH MILD HAEMOPHILIA A AND A FAMILIAL DISCREPANCY BETWEEN THE ONE‐STAGE AND TWO‐STAGE FACTOR VIII:C METHODSSemantic proximity Read ↗

Thrombin generation in haemophilia A patients with mutations causing factor VIII assay discrepancy.Semantic proximity Read ↗

Tyr346-->Cys mutation results in factor VIII:C assay discrepancy and a normal bleeding phenotype - is this mild haemophilia A?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.