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Article

A t(4;22) in a meningioma points to the localization of a putative tumor-suppressor gene.

American journal of human genetics - 1 Apr 1991

Lekanne Deprez R H, Groen N A, van Biezen N A, Hagemeijer A, van Drunen E, Koper J W, Avezaat C J, Bootsma D, Zwarthoff E C

Abstract excerpt

Cytogenetic analysis of meningioma cells from one particular patient (MN32) displayed the stem-line karyo-type 45, XY, -1, 4p+, 22q-, 22q+, which thus had rearrangements of both chromosomes 22. The 22q+ marker appeared as a dicentric: 22 pter----q11::1p11----qter. The reciprocal product of this translocation has presumably been lost because it lacked a centromere. The 22q- chromosome also appeared to have lost...

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Identifiers

PMID: 2014801
PMCID: PMC1682947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A t(4;22) in a meningioma points to the localization of a putative tumor-suppressor gene.PMID 2014801Read ↗

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