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Article

Evidence for an ependymoma tumour suppressor gene in chromosome region 22pter-22q11.2.

British journal of cancer - 1 Dec 1999

Hulsebos T J, Oskam N T, Bijleveld E H, Westerveld A, Hermsen M A, van den Ouweland A M, Hamel B C, Tijssen C C

Abstract excerpt

Ependymomas are glial tumours of the brain and spinal cord. The most frequent genetic change in sporadic ependymoma is monosomy 22, suggesting the presence of an ependymoma tumour suppressor gene on that chromosome. Clustering of ependymomas has been reported to occur in some families. From an earlier study in a family in which four cousins developed an ependymoma, we concluded that an ependymoma-susceptibility...

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Share to Central Nervous System Neoplasms
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 22

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Share to Genes, Tumor Suppressor

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Source

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Identifiers

PMID: 10584875
DOI: 10.1038/sj.bjc.6690822
PMCID: PMC2374323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for an ependymoma tumour suppressor gene in chromosome region 22pter-22q11.2.PMID 10584875Read ↗

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