Article
Molecular analysis of a myxoid chondrosarcoma with rearrangements of chromosomes 10 and 22.
Cancer genetics and cytogenetics - 1 Apr 1990
Shen W P, Young R F, Walter B N, Choi B H, Smith M, Katz J
Abstract excerpt
Myxoid chondrosarcoma is a rare tumor of adulthood. An associated nonrandom reciprocal translocation between chromosome 9 and 22 was previously reported in this tumor. We performed cytogenetic and molecular genetic analysis of a myxoid chondrosarcoma derived from the sphenoid bone. Using restriction fragment length polymorphism (RFLP) analysis, we demonstrated rearrangement and a possible allele loss close to the...
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