Article
Medulloblastoma harbor somatic mitochondrial DNA mutations in the D-loop region.
Journal of pediatric hematology/oncology - 1 Mar 2010
Lueth Maria, von Deimling Andreas, Pietsch Torsten, Wong Lee-Jun, Kurtz Andreas, Henze Guenter, Driever Pablo Hernáiz
Abstract excerpt
Despite the growing knowledge on molecular risk factors of the most common malignant brain tumor in childhood, medulloblastoma, its biology remains only partially understood. A previous study investigating the entire mitochondrial genome of medulloblastoma revealed a number of somatic mutations i...
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