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Proteomic and Mitochondrial Genomic Analyses of Pediatric Brain Tumors.

Molecular neurobiology - 1 Dec 2015

Luna Brenda, Bhatia Sanjiv, Yoo Changwon, Felty Quentin, Sandberg David I, Duchowny Michael, Khatib Ziad, Miller Ian, Ragheb John, Prasanna Jayakar, Roy Deodutta

Abstract excerpt

The molecular mechanism unraveling why a particular type of pediatric brain tumor (pBT) behaves so differently from child to child or genetic/epigenetic changes in the mitochondrial genome vary from tumor to tumor is not clearly understood. Despite the identification of mitochondrial DNA (mtDNA) mutations in different types of pBT, the contribution of mitochondrial dysfunction-related genes or proteins that are...

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PMID: 25341474
DOI: 10.1007/s12035-014-8930-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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