Article
The Staphylococcus aureus siderophore receptor HtsA undergoes localized conformational changes to enclose staphyloferrin A in an arginine-rich binding pocket.
The Journal of biological chemistry - 9 Apr 2010
Grigg Jason C, Cooper John D, Cheung Johnson, Heinrichs David E, Murphy Michael E P
Abstract excerpt
Staphylococcus aureus uses several efficient iron acquisition strategies to overcome iron limitation. Recently, the genetic locus encoding biosynthetic enzymes for the iron chelating molecule, staphyloferrin A (SA), was determined. S. aureus synthesizes and secretes SA into its environment to sca...
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