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Article

The oxidative stress regulator, PerR, is required for staphyloferrin B-mediated iron acquisition in Staphylococcus aureus.

Journal of bacteriology - 20 Aug 2026

Sheikh Alexander A, Flannagan Ronald S, Nicholson Nathan J, Jarycki Natalie, Fabelurin Racheal O, Lewis Ian A, Heinrichs David E

Abstract excerpt

Staphylococcus aureus is a globally prevalent gram-positive pathogen that can cause numerous types of infection. Due to host nutritional immunity and iron (Fe) sequestration, S. aureus experiences Fe limitation during infection. To overcome this, S. aureus expresses an arsenal of Fe acquisition systems whose expression is coordinated through the Fe-binding transcriptional regulator, Fur. Here, from a screen to...

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Citrates
Cytochrome b Group
Gene Expression Regulation, Bacterial
Iron
Oxidative Stress

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Staphylococcal Infections

Staphylococcus aureus

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PMID: 42446995
DOI: 10.1128/jb.00149-26
PMCID: PMC13492143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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The oxidative stress regulator, PerR, is required for staphyloferrin B-mediated iron acquisition in Staphylococcus aureus.PMID 42446995Read ↗

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