Article
The effect of c-myc on stem cell fate influences skin tumor phenotype.
Molecular carcinogenesis - 1 Apr 2010
Honeycutt Kimberly A, Waikel Rebekah L, Koster Maranke I, Wang Xiao-Jing, Roop Dennis R
Abstract excerpt
Nonmelanoma skin cancers (NMSCs) consist of a variety of tumor types including basal cell carcinoma, squamous cell carcinoma, a variety of hair follicle tumors, and sebaceous gland tumors. Genetic alterations that alter the fate of multipotent stem cells are believed to influence NMSC phenotype. We previously generated a transgenic mouse line which constitutively expressed c-myc under the control of the K14...
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