Article
Reconstitution of natural killer cell receptors influences natural killer activity and relapse rate after haploidentical transplantation of T- and B-cell depleted grafts in children.
Haematologica - 1 Aug 2010
Pfeiffer Matthias M, Feuchtinger Tobias, Teltschik Heiko-Manuel, Schumm Michael, Müller Ingo, Handgretinger Rupert, Lang Peter
Abstract excerpt
BACKGROUND: Natural killer cells have been demonstrated to exert remarkable graft-versus-leukemia effects after haploidentical transplantation. Acquisition of both, inhibiting and activating, receptors on developing natural killer cells is an important step in their functional maturation. Here, w...
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