Article
Prevalence of mitochondrial tRNA gene mutations and their association with specific clinical phenotypes in patients with type 2 diabetes mellitus of Coimbatore.
Genetic testing and molecular biomarkers - 1 Feb 2010
Duraisamy Pradeepa, Elango Santhini, Vishwanandha Vijaya Padma, Balamurugan Ramanathan
Abstract excerpt
The association of mitochondrial DNA mutation with type 2 diabetes mellitus (T2DM) is well established. In this study we aimed to assess the frequency of A3243G, A8296G, and other mitochondrial mutations with reference to clinical features in the diabetic population of Coimbatore, India. The study group included 150 patients (89 women and 61 men) with T2DM, whereas the control group included 100 nondiabetic...
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