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Mitochondrial and nuclear gene mutations in the type 2 diabetes patients of Coimbatore population.

Molecular and cellular biochemistry - 1 Dec 2010

Vijaya Padma Viswanadha, Anitha Shobana, Santhini Elango, Pradeepa Duraisamy, Tresa Dominic, Ganesan Perumal, Ishwarya Periyasamy, Balamurugan Ramanathan, Balakrishnan Ramanathan

Abstract excerpt

Involvement of mitochondrial and nuclear gene mutations in the development of type 2 diabetes (T2D) has been established well in various populations around the world. Previously, we have found the mitochondrial A>G transition at nucleotide position 3243 and 8296 in the T2D patients of Coimbatore population. This study is aimed to screen for the presence of various mitochondrial and nuclear DNA mutations in the...

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PMID: 20730618
DOI: 10.1007/s11010-010-0576-5

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