Article
[Genetic background of mitochondrial diabetes].
Casopis lekaru ceskych - 1 Jan 2007
Vanková M, Lukásová P, Zemanová A, Vcelák J, Vejrazková D, Mazura I, Bendlová B
Abstract excerpt
Diabetes mellitus type 2 represents a heterogenous disease characterized by impaired glucose homeostasis. The disorder clusters in families suggesting genetic disposition, however the mechanism underlying is unknown. Many studies show more frequent maternal transmission of diabetes in the families. One of huge range of explanation is exclusively maternal transmission of mitochondria. Mitochondria are power...
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