Article
Geographic distribution of fluoroquinolone-resistant Escherichia coli strains in Asia.
International journal of antimicrobial agents - 1 Apr 2010
Uchida Yujiro, Mochimaru Tomomi, Morokuma Yuiko, Kiyosuke Makiko, Fujise Masako, Eto Fujiko, Harada Yukiko, Kadowaki Masako, Shimono Nobuyuki, Kang Dongchon
Abstract excerpt
Fluoroquinolone (FQ) resistance is usually caused by point mutations within the quinolone resistance-determining regions (QRDRs) of gyrA, gyrB, parC and/or parE. However, little is known about the worldwide increase in FQ-resistant Escherichia coli or, more specifically, about the geographical distribution of QRDR mutations and the clonal spread of isolates. In this study, we analysed 68 FQ-resistant E. coli...
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