Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

RecQ-dependent death-by-recombination in cells lacking RecG and UvrD.

DNA repair - 4 Apr 2010

Fonville Natalie C, Blankschien Matthew D, Magner Daniel B, Rosenberg Susan M

Abstract excerpt

Maintenance of genomic stability is critical for all cells. Homologous recombination (HR) pathways promote genome stability using evolutionarily conserved proteins such as RecA, SSB, and RecQ, the Escherichia coli homologue of five human proteins at least three of which suppress genome instability and cancer. A previous report indicated that RecQ promotes the net accumulation in cells of intermolecular HR...

Topics

DNA Helicases
Escherichia coli
Escherichia coli Proteins
Mutation
RecQ Helicases
Recombination, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20138014
DOI: 10.1016/j.dnarep.2009.12.019
PMCID: PMC2846991

Genes

SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RecQ-dependent death-by-recombination in cells lacking RecG and UvrD.PMID 20138014Read ↗

RecQ promotes toxic recombination in cells lacking recombination intermediate-removal proteins.Semantic proximity Read ↗

Unique and important consequences of RECQ1 deficiency in mammalian cellsSemantic proximity Read ↗

The RecQ4 orthologue Hrq1 is critical for DNA interstrand cross-link repair and genome stability in fission yeast.Semantic proximity Read ↗

ATRX and RECQ5 define distinct homologous recombination subpathwaysSemantic proximity Read ↗

RecG helicase promotes DNA double-strand break repair.Semantic proximity Read ↗

recF-dependent recombination as a SOS function.Semantic proximity Read ↗

Functional fine-tuning between bacterial DNA recombination initiation and quality control systems.Semantic proximity Read ↗

Resolving Toxic DNA repair intermediates in every E. coli replication cycle: critical roles for RecG, Uup and RadD.Semantic proximity Read ↗

RecO acts with RecF and RecR to protect and maintain replication forks blocked by UV-induced DNA damage in Escherichia coli.Semantic proximity Read ↗

RdgB acts to avoid chromosome fragmentation in Escherichia coli.Semantic proximity Read ↗

Modulation of DNA damage tolerance in Escherichia coli recG and ruv strains by mutations affecting PriB, the ribosome and RNA polymerase.Semantic proximity Read ↗

RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.