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CYP17 (T-34C) and CYP19 (Trp39Arg) polymorphisms and their cooperative effects on breast cancer susceptibility.

In vivo (Athens, Greece) - 1 Jan 2000

Tüzüner Bora M, Oztürk Tülin, Kisakesen Halil I, Ilvan Sennur, Zerrin Calay, Oztürk Oğuz, Isbir Turgay

Abstract excerpt

BACKGROUND: Breast cancer is the commonest cancer among women in industrialized countries. Most sporadic breast carcinomas are likely to be caused by low-penetrance genes. Genes encoding enzymes involved in estrogen and carcinogen metabolism are among these low-penetrance genes. In this study, for the first time the T/C (A1/A2) polymorphism at the 5' untranslated region (UTR) of CYP17 and the Arg/Trp (T/C)...

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PMID: 20133979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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