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Article

CYP17 (T34C), CYP19 (Trp39Arg), and FGFR2 (C906T) polymorphisms and the risk of breast cancer in south Indian women.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000

Samson Mani, Rama Ranganathan, Swaminathan Rajaraman, Sridevi Veluswami, Nancy Karunakaran Nirmala, Rajkumar Thangarajan

Abstract excerpt

Breast cancer is initiated by exposure to endogenous and exogenous estrogens. A case-control (n= 250-500) study was undertaken to investigate the role of Single Nucleotide Polymorphisms (SNP's) in CYP17 (T34C), CYP19 (Trp39Arg) and FGFR2(C906T). Genotyping was done using the Taqman allelic discrimination assay for CYP17 (T34C) and FGFR2 (T906C) and PCR-CTPP for CYP19 (Trp39Arg). There was a significant protective...

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Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Receptor, Fibroblast Growth Factor, Type 2

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PMID: 19469636

Genes

FGFR2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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