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Article

The inorganic pyrophosphate transporter ANK preserves the differentiated phenotype of articular chondrocyte.

The Journal of biological chemistry - 2 Apr 2010

Cailotto Frederic, Sebillaud Sylvie, Netter Patrick, Jouzeau Jean-Yves, Bianchi Arnaud

Abstract excerpt

The differentiated phenotype of chondrocyte is lost in pathological situations and after interleukin (IL)-1beta challenge. Wnt proteins and the inorganic pyrophosphate (PP(i)) transporter Ank regulate the differentiation process in many cell types. We investigated the possible contribution of Ank...

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Share to Cartilage, Articular
Share to Chondrocytes
Share to Collagen Type II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Culture Media, Conditioned

Share to Diphosphates

Share to JNK Mitogen-Activated Protein Kinases

Share to Phosphate Transport Proteins

Share to SOX9 Transcription Factor

Source

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Identifiers

PMID: 20133941
DOI: 10.1074/jbc.M109.050534
PMCID: PMC2856265

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20133941-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The inorganic pyrophosphate transporter ANK preserves the differentiated phenotype of articular chondrocyte.PMID 20133941Read ↗

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Differential requirements for IKKalpha and IKKbeta in the differentiation of primary human osteoarthritic chondrocytes.Semantic proximity Read ↗

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