Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modulation of histamine H(3) receptor function by monovalent ions.

Neuroscience letters - 19 Mar 2010

Schnell David, Seifert Roland

Abstract excerpt

Monovalent ions differently affect ligand binding to G protein-coupled receptors (GPCRs) by as yet poorly defined mechanisms. In particular, NaCl often decreases the affinity of agonists but increases it for antagonists. We examined the effect of various monovalent ions on human histamine H(3) receptor (hH(3)R), co-expressed with mammalian G proteins (Galpha(i1), Galpha(i2), Galpha(i3) or Galpha(o1), and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anions
Share to Cell Line
Share to GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insecta

Share to Mutation

Share to Radioligand Assay

Share to Signal Transduction

Source

Identifiers

PMID: 20132865
DOI: 10.1016/j.neulet.2010.01.065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modulation of histamine H(3) receptor function by monovalent ions.PMID 20132865Read ↗

Pharmacological Characterization of Human Histamine Receptors and Histamine Receptor Mutants in the Sf9 Cell Expression System.Semantic proximity Read ↗

Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H1 receptors by Na.Semantic proximity Read ↗

Molecular basis of kainate receptor modulation by sodium.Semantic proximity Read ↗

Conserved lysin and arginin residues in the extracellular loop of P2X(3) receptors are involved in agonist binding.Semantic proximity Read ↗

A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens.Semantic proximity Read ↗

Differential responses of an invariant region in the ectodomain of three glycoprotein hormone receptors to mutagenesis and assay conditions.Semantic proximity Read ↗

Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor.Semantic proximity Read ↗

Pharmacological characterization of seven human histamine H <sub>3</sub> receptor isoformsSemantic proximity Read ↗

External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probability.Semantic proximity Read ↗

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3.Semantic proximity Read ↗

Generation and characterization of highly constitutive active histamine H3 receptors.Semantic proximity Read ↗

Molecular determinants of ligand binding to H4R species variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.