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Article

SNVHMM: predicting single nucleotide variants from next generation sequencing.

BMC bioinformatics - 15 Jul 2013

Bian Jiawen, Liu Chenglin, Wang Hongyan, Xing Jing, Kachroo Priyanka, Zhou Xiaobo

Abstract excerpt

BACKGROUND: The rapid development of next generation sequencing (NGS) technology provides a novel avenue for genomic exploration and research. Single nucleotide variants (SNVs) inferred from next generation sequencing are expected to reveal gene mutations in cancer. However, NGS has lower sequence coverage and poor SNVs detection capability in the regulatory regions of the genome. Post probabilistic based methods...

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Identifiers

PMID: 23855743
DOI: 10.1186/1471-2105-14-225
PMCID: PMC3718670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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