Article
Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts.
Molecular psychiatry - 1 Jun 2010
Muglia P, Tozzi F, Galwey N W, Francks C, Upmanyu R, Kong X Q, Antoniades A, Domenici E, Perry J, Rothen S, Vandeleur C L, Mooser V, Waeber G, Vollenweider P, Preisig M, Lucae S, Müller-Myhsok B, Holsboer F, Middleton L T, Roses A D
Abstract excerpt
Major depressive disorder (MDD) is a highly prevalent disorder with substantial heritability. Heritability has been shown to be substantial and higher in the variant of MDD characterized by recurrent episodes of depression. Genetic studies have thus far failed to identify clear and consistent evidence of genetic risk factors for MDD. We conducted a genome-wide association study (GWAS) in two independent datasets....
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