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Article

Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress.

American journal of physiology. Cell physiology - 1 Aug 2007

Sautin Yuri Y, Nakagawa Takahiko, Zharikov Sergey, Johnson Richard J

Abstract excerpt

Uric acid is considered a major antioxidant in human blood that may protect against aging and oxidative stress. Despite its proposed protective properties, elevated levels of uric acid are commonly associated with increased risk for cardiovascular disease and mortality. Furthermore, recent experi...

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Identifiers

PMID: 17428837
DOI: 10.1152/ajpcell.00600.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17428837-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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