A Simple Isothermal DNA Amplification Method to Screen Black Flies for Onchocerca volvulus Infection

doi:10.1371/journal.pone.0108927

Article

A Simple Isothermal DNA Amplification Method to Screen Black Flies for Onchocerca volvulus Infection

9 Oct 2014

Abstract excerpt

Onchocerciasis is a debilitating neglected tropical disease caused by infection with the filarial parasite Onchocerca volvulus. Adult worms live in subcutaneous tissues and produce large numbers of microfilariae that migrate to the skin and eyes. The disease is spread by black flies of the genus Simulium following ingestion of microfilariae that develop into infective stage larvae in the insect. Currently,...

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