Article
Onchocerca volvulus: limited heterogeneity in the nuclear and mitochondrial genomes.
Experimental parasitology - 1 Dec 1999
Keddie E M, Higazi T, Boakye D, Merriweather A, Wooten M C, Unnasch T R
Abstract excerpt
West African populations of Onchocerca volvulus endemic to the rain forest and savanna bioclimes of West Africa differ in their ability to induce ocular disease in infected individuals. In recent years, both clinical- and animal-model-based studies have implicated particular parasite antigens in the development of ocular onchocerciasis. To test the hypothesis that the difference in pathogenic potential of...
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