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Article

Role of apoptosis in pulmonary hypertension: from experimental models to clinical trials.

Pharmacology & therapeutics - 1 Apr 2010

Jurasz Paul, Courtman David, Babaie Saeid, Stewart Duncan J

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a progressive and lethal disease that has a strong female predominance, often affecting the young. Current therapies are mostly vasodilator agents, and while mainly addressing the endothelial dysfunction that has been widely reported in this disease, they...

Read the complete abstract on PubMed

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Share to Apoptosis
Share to Bone Morphogenetic Protein Receptors, Type II
Share to Clinical Trials as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Hypertension, Pulmonary

Share to Nitric Oxide Synthase

Share to Stem Cell Transplantation

Source

Identifiers

PMID: 20117135
DOI: 10.1016/j.pharmthera.2009.12.006

Genes

PAH
BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20117135-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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