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Article

Role of apoptosis in pulmonary hypertension: from experimental models to clinical trials.

Pharmacology & therapeutics - 1 Apr 2010

Jurasz Paul, Courtman David, Babaie Saeid, Stewart Duncan J

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a progressive and lethal disease that has a strong female predominance, often affecting the young. Current therapies are mostly vasodilator agents, and while mainly addressing the endothelial dysfunction that has been widely reported in this disease, they may be less effective in treating arterial remodeling. The lung pathology of PAH is characterized by medial hypertrophy...

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Source

Identifiers

PMID: 20117135
DOI: 10.1016/j.pharmthera.2009.12.006

Genes

PAH
BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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