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Article

Molecular pathogenesis of pulmonary arterial hypertension.

The Journal of clinical investigation - 1 Dec 2012

Rabinovitch Marlene

Abstract excerpt

Recent clinical and experimental studies are redefining the cellular and molecular bases of pulmonary arterial hypertension (PAH). The genetic abnormalities first identified in association with the idiopathic form of PAH--together with a vast increase in our understanding of cell signaling, cell transformation, and cell-cell interactions; gene expression; microRNA processing; and mitochondrial and ion channel...

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Topics

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Share to Bone Morphogenetic Protein Receptors, Type II
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension, Pulmonary

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Share to Receptors, Serotonin

Share to Serotonin Plasma Membrane Transport Proteins

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Source

Open in PubMed Open full text

Identifiers

PMID: 23202738
DOI: 10.1172/JCI60658
PMCID: PMC3533531

Genes

PAH
BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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