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Article

Pulmonary hypertension due to BMPR2 mutation: a new paradigm for tissue remodeling?

Proceedings of the American Thoracic Society - 1 Nov 2006

Morrell Nicholas W

Abstract excerpt

Genetic studies in familial pulmonary arterial hypertension (FPAH) have revealed heterozygous germline mutations in the bone morphogenetic protein type II receptor (BMPR-II), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. PAH is characterize...

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Share to Apoptosis
Share to Bone Morphogenetic Protein 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension, Pulmonary

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Share to Muscle, Smooth, Vascular

Share to Mutation, Missense

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 17065373
DOI: 10.1513/pats.200605-118SF

Genes

PAH
BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17065373-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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