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Article

A tag at the carboxy terminus prevents membrane integration of VDAC1 in mammalian mitochondria.

Journal of molecular biology - 19 Mar 2010

Kozjak-Pavlovic Vera, Ross Katharina, Götz Monika, Goosmann Christian, Rudel Thomas

Abstract excerpt

beta-Barrel proteins are found in the outer membranes of bacteria, chloroplasts and mitochondria. The evolutionary conserved sorting and assembly machinery (SAM complex) assembles mitochondrial beta-barrel proteins, such as voltage-dependent anion-selective channel 1 (VDAC1), into complexes in the outer membrane by recognizing a sorting beta-signal in the carboxy-terminal part of the protein. Here we show that in...

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Identifiers

PMID: 20117113
DOI: 10.1016/j.jmb.2010.01.047

Genes

VDAC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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