Article
The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria.
The Journal of cell biology - 5 Jan 2004
Gentle Ian, Gabriel Kipros, Beech Peter, Waller Ross, Lithgow Trevor
Abstract excerpt
Integral proteins in the outer membrane of mitochondria control all aspects of organelle biogenesis, being required for protein import, mitochondrial fission, and, in metazoans, mitochondrial aspects of programmed cell death. How these integral proteins are assembled in the outer membrane had been unclear. In bacteria, Omp85 is an essential component of the protein insertion machinery, and we show that members of...
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